*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Tetraethylene glycol (TEG) linker serves as a versatile polyether spacer in bioconjugation and polymer synthesis. The core process involves etherification to ensure high purity. Its molecular formula is <strong>C8H18O5</strong> with CAS No. <strong>112-34-5</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Antibody-Drug Conjugates (ADCs):</strong> Provides optimal distance between cytotoxic payloads and antibody backbones.</li>
<li><strong>Peptide Synthesis:</strong> Acts as a hydrophilic spacer to enhance solubility and reduce steric hindrance.</li>
<li><strong>Polymer Chemistry:</strong> Utilized in synthesizing PEGylated polymers for controlled release systems.</li>
</ul>
<h3>Precautions</h3>
<p>Store in tightly sealed containers at 2-8°C away from moisture. Use appropriate PPE to prevent skin contact; avoid inhalation of vapors during handling.</p>