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<h3>Overview</h3>
<p><strong>Tebipenem</strong> is a novel oral carbapenem antibiotic developed to address multidrug-resistant Gram-negative infections. Its core synthesis involves advanced chiral catalysis to ensure high optical purity. The molecular formula is C18H27N5O6S, and the CAS number is 149048-68-0.</p>
<h3>Application</h3>
<ul>
<li>Hospital settings for treating complicated urinary tract infections (cUTIs).</li>
<li>Pediatric pneumonia management as an oral alternative to intravenous therapy.</li>
<li>Outpatient care for resistant Enterobacteriaceae strains.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with severe hypersensitivity to carbapenems. Requires strict temperature control during storage at 2°C–8°C to maintain stability. Clinical use must be monitored for potential CNS adverse effects in high-dose regimens.</p>