Product Description
Reference Standards &Impurity
AI Product Description
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Taurodeoxycholic Acid Sodium Salt is a vital bile acid derivative widely utilized in biochemical research and pharmaceutical development. Chemically, it serves as the sodium salt of taurodeoxycholic acid, a secondary bile acid formed through the bacterial dehydroxylation of chenodeoxycholic acid in the human intestine. Its molecular formula is C26H43NNaO6S, and it is identified by the CAS Registry Number 508-71-0. This compound appears as a white to off-white powder that is highly soluble in water, forming clear solutions at physiological pH levels, which makes it ideal for various aqueous-based experimental protocols.
The primary application of Taurodeoxycholic Acid Sodium Salt lies in the study of lipid metabolism and gastrointestinal physiology. Researchers frequently employ it as a standard reference material to analyze bile acid profiles using techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry. Furthermore, it plays a crucial role in investigating the solubilization properties of lipids, aiding in the formulation of drug delivery systems where membrane permeability and micelle formation are critical factors. In cell biology, this reagent is often used to modulate membrane fluidity or to induce specific cellular responses related to bile acid signaling pathways.
Beyond basic research, this compound has implications in understanding cholestatic liver diseases and metabolic disorders. By mimicking natural bile acids, it helps scientists explore mechanisms of bile acid toxicity and transport across biological membranes. Additionally, its surfactant-like characteristics make it useful in preparing emulsions for in vitro digestion studies, allowing researchers to simulate the breakdown of dietary fats under controlled conditions. The availability of this sodium salt ensures stability and ease of handling compared to its free acid form, facilitating reproducible results across diverse laboratories. As a key tool in metabolic profiling and drug discovery, Taurodeoxycholic Acid Sodium Salt continues to support advancements in hepatology, pharmacology, and nutritional science, providing essential insights into human health and disease mechanisms.