Product Description
| ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Chemical Properties |
| Boiling point |
651.6±55.0 °C(Predicted) |
| density |
1.34±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. |
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| pka |
4.66±0.10(Predicted) |
AI Product Description
*The following content is generated by AI and is for reference only.
The compound supplied as ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate is a sophisticated heterocyclic molecule belonging to the pyrazolopyridine family. While specific commercial catalogs may vary in listing its exact CAS number due to its status as a specialized research intermediate rather than a bulk commodity chemical, it is structurally characterized by a fused bicyclic core featuring a pyrazole ring fused to a dihydropyridinone system. The molecular formula typically aligns with C21H19N3O4, reflecting the presence of an ethyl ester group at position three, a methoxy-substituted phenyl ring at position one, and an amino-substituted phenyl moiety at position six. This unique substitution pattern renders the molecule highly valuable for medicinal chemistry applications, particularly in the synthesis of novel kinase inhibitors and anticancer agents.
Pyrazolopyridine derivatives are renowned for their potent biological activities, including anti-inflammatory, antiviral, and cytotoxic properties. The introduction of the 4-aminophenyl group suggests potential utility in targeting specific protein kinases involved in cell proliferation pathways, making this compound a critical building block for drug discovery programs focused on oncology. Researchers utilize this substrate to construct more complex pharmacophores through various coupling reactions, such as amide formation or reductive amination, leveraging the reactive amino functionality. Furthermore, the 4-methoxyphenyl and ethyl ester groups offer versatile handles for structural modification, allowing chemists to fine-tune the physicochemical properties, such as lipophilicity and metabolic stability, of the final drug candidates.
In laboratory settings, high-purity samples of this material are essential for conducting Structure-Activity Relationship (SAR) studies. These investigations aim to optimize the binding affinity and selectivity of the compounds against disease targets. Due to the complexity of its synthesis, which often involves multistep cyclization strategies under controlled conditions, reliable supply chains for this specific analog are crucial for advancing preclinical research. Consequently, suppliers specializing in organic intermediates provide this compound to academic institutions and pharmaceutical companies seeking to accelerate the development of next-generation therapeutic agents targeting cancer and other chronic diseases.