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Basic Info
CAS Number
/
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Samples Provided
NO
Packaging & Delivery
Packaging Specification
25KG/DRUM
Product Description
USP15
AI Product Description
*The following content is generated by AI and is for reference only.
Sulphamerazine Sodium is the sodium salt derivative of Sulphamerazine, a well-established sulfonamide antibiotic belonging to the sulfa drug class. Its molecular formula is C₁₁H₁₂N₄NaO₃S, reflecting the addition of a sodium ion to the parent sulfonamide structure, which significantly enhances its water solubility compared to the free acid form. The compound is registered under CAS number 127-69-5. This chemical modification allows for rapid dissolution in aqueous solutions, making it particularly suitable for intravenous or oral administration in veterinary medicine where quick therapeutic blood levels are required.
The primary application of Sulphamerazine Sodium lies in veterinary pharmacology, specifically for the treatment and prevention of bacterial infections in livestock, including cattle, swine, and poultry. It functions by inhibiting the synthesis of folic acid in susceptible bacteria; specifically, it acts as a competitive antagonist against para-aminobenzoic acid (PABA), an essential precursor for bacterial folate production. By disrupting this metabolic pathway, the drug effectively halts bacterial replication and growth. It is commonly utilized to combat infections caused by Gram-positive and some Gram-negative organisms, such as those responsible for respiratory diseases, enteritis, and urinary tract infections in animals.
Due to concerns regarding antibiotic resistance and residue accumulation in food-producing animals, the use of sulfonamides like Sulphamerazine Sodium is strictly regulated globally. Regulatory bodies enforce mandatory withdrawal periods before meat or milk from treated animals can enter the human food supply chain to ensure consumer safety. While newer antibiotics have emerged, Sulphamerazine Sodium remains a valuable tool in specific therapeutic protocols due to its broad-spectrum efficacy and cost-effectiveness. However, its administration requires careful dosage calculation to avoid toxicity, which can manifest as crystalluria, hemolytic anemia, or bone marrow suppression if overdosed. Overall, it serves as a critical component in modern veterinary antimicrobial strategies when used responsibly and in compliance with international health standards.
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