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Basic Info
CAS Number
/
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Samples Provided
NO
Packaging & Delivery
Packaging Specification
25KG/DRUM
Product Description
EP7
AI Product Description
*The following content is generated by AI and is for reference only.
Sulphamerazine Base is a fundamental intermediate in the pharmaceutical industry, primarily serving as a precursor for the synthesis of various sulphonamide antibiotics. Chemically known as 2-methylsulphanilamide or N1-(3-methyl-4-sulfamoylphenyl)amine, this compound belongs to the sulfonamide class of drugs, which were among the first effective systemic antimicrobial agents discovered. Its molecular formula is C11H12N4O2S, and it is uniquely identified by the CAS registry number 80-35-1. The substance typically appears as a pale yellow to white crystalline powder, characterized by low solubility in water but good solubility in dilute acids and organic solvents like ethanol.
In its base form, Sulphamerazine acts as a critical building block rather than a final therapeutic product itself. It is extensively utilized in laboratory research and industrial manufacturing to produce specific derivatives that exhibit enhanced antibacterial properties. Historically, sulphonamides played a pivotal role in treating bacterial infections such as pneumonia, meningitis, and urinary tract infections before the widespread adoption of penicillin and modern antibiotics. While direct clinical use of Sulphamerazine base is limited due to potential toxicity and resistance issues, its structural framework remains vital for developing new generation antimicrobials.
The compound functions by inhibiting bacterial dihydropteroate synthase, an enzyme essential for folic acid synthesis in microorganisms. By blocking this pathway, it prevents bacteria from replicating and spreading, thereby controlling infection. Beyond medical applications, Sulphamerazine Base is also employed in veterinary medicine, though regulations have tightened regarding its use in food-producing animals due to residue concerns. Researchers continue to study its derivatives to overcome antibiotic resistance mechanisms. Overall, Sulphamerazine Base represents a cornerstone in medicinal chemistry, bridging historical antibiotic development with ongoing efforts to combat resistant pathogens through innovative drug design.
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