Approval license No: gyzz H10890014
Constitutional formula: C20H18N8O4S2ZN 2H2O
Category: Sulfa Antibiotics
Common drug agents: slurry powder plastics
Package: 500g/1000g/aluminum barrel
*The following content is generated by AI and is for reference only.
Sulfadiazine zinc, chemically known as zinc sulfadiazine, is a widely recognized pharmaceutical agent and veterinary drug primarily utilized for its potent antibacterial properties. Its molecular formula is C10H9N4O2S2Zn, reflecting the coordination of the zinc ion with two molecules of sulfadiazine. The substance is identified by the CAS number 128-08-5. This compound serves as a topical antimicrobial, particularly effective against a broad spectrum of Gram-positive and Gram-negative bacteria, including *Staphylococcus aureus* and *Pseudomonas aeruginosa*.
The primary clinical application of Sulfadiazine zinc lies in the management of burn injuries and chronic wounds. Unlike silver sulfadiazine, which is more common, this formulation offers a distinct therapeutic profile where the zinc component plays a dual role: it not only enhances the delivery of the sulfa drug but also actively promotes tissue regeneration and wound healing. Zinc is essential for cellular proliferation and collagen synthesis, making this combination highly beneficial for accelerating the closure of superficial burns and preventing secondary infections in compromised skin tissues. Furthermore, it acts as an effective barrier against bacterial colonization while maintaining a moist wound environment conducive to healing.
In veterinary medicine, the product is frequently employed to treat skin infections in various animals, ranging from dogs and cats to livestock, addressing conditions such as pyoderma and dermatitis. Its mechanism involves inhibiting dihydropteroate synthase, a key enzyme in bacterial folate synthesis, thereby halting bacterial growth. While generally well-tolerated topically, patients may experience local irritation or allergic reactions, necessitating careful monitoring during prolonged use. The stability and efficacy of Sulfadiazine zinc make it a valuable asset in both human and animal healthcare settings, offering a reliable solution for infected wounds where rapid bacterial control and tissue repair are critical. As with all antimicrobial agents, judicious usage is recommended to mitigate the risk of developing resistant bacterial strains, ensuring long-term therapeutic effectiveness.