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Basic Info
CAS Number
N/A
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Sulfachlorpyridazine is a synthetic sulfonamide antibiotic belonging to the broad class of sulfa drugs, which function as competitive inhibitors of dihydropteroate synthase in the bacterial folate synthesis pathway. With the Chemical Abstracts Service (CAS) registry number 127-69-5, this compound features the molecular formula C10H10ClN3O2S and a molecular weight of approximately 271.7 g/mol. Structurally, it consists of a pyridazine ring substituted with a chlorine atom and linked to a sulfonamide group, distinguishing it from other common sulfonamides like sulfadiazine or sulfamerazine by its specific heterocyclic core.
Primarily utilized in veterinary medicine, Sulfachlorpyridazine serves as an effective treatment for various bacterial infections in livestock, including poultry, swine, and cattle. It is particularly noted for its efficacy against Gram-positive bacteria such as Streptococcus and Staphylococcus species, as well as certain Gram-negative organisms like E. coli and Salmonella. Due to its pharmacokinetic profile, which includes good tissue penetration and a relatively long half-life compared to some earlier generation sulfonamides, it allows for less frequent dosing regimens in animal husbandry. This characteristic makes it a valuable tool in preventing and controlling respiratory diseases, enteric infections, and systemic septicemias in farm animals.
In addition to therapeutic applications, the compound has historically been used in combination with pyrimethamine or other diaminopyrimidines to enhance antibacterial potency through synergistic inhibition of sequential steps in folate metabolism. While human use is extremely limited due to the availability of safer alternatives and potential toxicity concerns, it remains a significant agent in global food production safety. The drug is often administered via feed or water additives to manage herd health proactively. However, strict withdrawal periods are enforced before meat or milk products enter the food supply chain to prevent residue accumulation in consumers. Regulatory agencies worldwide monitor its usage closely to ensure compliance with maximum residue limits (MRLs). As antimicrobial resistance patterns evolve, Sulfachlorpyridazine continues to be studied for its role in integrated disease management strategies within the agricultural sector, balancing efficacy with responsible stewardship of veterinary antibiotics.
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