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<h3>Overview</h3>
<p><strong>Spacer Phosphoramidite C3</strong> is a specialized linker used in solid-phase oligonucleotide synthesis. It introduces a three-carbon alkyl chain spacer to modulate hybridization properties. The molecular formula is typically C15H26N2O4PSi, with CAS number 86709-28-2.</p>
<h3>Application</h3>
<ul>
<li>DNA microarray fabrication for enhanced probe stability.</li>
<li>Antisense therapy to reduce non-specific binding.</li>
<li>In vitro diagnostics requiring precise melting temperature control.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C. Avoid moisture exposure to prevent hydrolysis. Use appropriate PPE due to potential irritancy; not for direct clinical administration without formulation.</p>