*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Sotalol is a non-selective beta-blocker with class III antiarrhythmic properties, synthesized via <strong>chiral resolution</strong> of sulfonamide intermediates. Its molecular formula is <strong>C12H20N2O4S</strong> (CAS: 59456-01-8).</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Production of generic antiarrhythmic tablets for ventricular arrhythmias.</li>
<li><strong>Research & Development:</strong> Use as a reference standard in cardiac electrophysiology studies.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated in patients with QT prolongation or severe renal impairment. Store at controlled room temperature (20-25°C) in dry, light-resistant containers to maintain stability.</p>