*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Sorafenib tosylate is the <strong>tosylate salt form</strong> of the multikinase inhibitor Sorafenib. Its molecular formula is <strong>C21H16ClF3N4O·C7H8O3S</strong> with CAS No. <strong>284461-73-0</strong>. This compound is synthesized via acid-base reaction between sorafenib free base and p-toluenesulfonic acid, enhancing stability for pharmaceutical formulations.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology Manufacturing:</strong> Used as API in hepatocellular carcinoma and renal cell carcinoma therapies.</li>
<li><strong>Research & Development:</strong> Serves as a reference standard for kinase inhibition assays.</li>
<li><strong>Pharmaceutical Formulation:</strong> Utilized in tablet production to improve solubility and bioavailability.</li>
</ul>
<h3>Precautions</h3>
<p>Storage requires controlled temperature (25°C) in dry, light-resistant containers. Handling demands PPE due to potential cytotoxicity; avoid inhalation or skin contact. Clinical use is restricted to oncology indications under strict medical supervision.</p>