Sorafenib toluenesulfonate is a synthetic compound of sorafenib that targets growth signals and angiogenesis. Sorafenib blocks the enzyme RAF kinase, which is a key component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; In addition, sorafenib inhibits VEGFR-2/PDGFR- β Signal cascade, thereby blocking tumor angiogenesis.