White or off-white powder, without smell but with hygroscopicity; disperses in water into sticky colloidal solution; insoluble in ethanol or diethyl ether.
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Sodium Starch Glycolate is a superdisintegrant derived from starch via etherification with sodium hydroxide and 2-chloroacetic acid. It functions by rapid wicking action to facilitate tablet disintegration. <strong>Molecular Formula</strong>: (C6H10O5)n·Na; <strong>CAS No.</strong>: 9005-40-7.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceuticals: Immediate-release tablets as primary disintegrant.</li>
<li>Oral Solid Dosage: Enhances dissolution rates of poorly soluble APIs.</li>
<li>Industrial Chemistry: Thickening agent in aqueous formulations.</li>
</ul>
<h3>Precautions</h3>
<p>Store in cool, dry conditions below 25°C to prevent clumping. Avoid inhalation of dust; wear appropriate PPE during handling. Not suitable for parenteral or ophthalmic preparations due to potential irritation.</p>