Product Description
Sodium 5-amino-2-hydroxybenzoate、35589-28-7
AI Product Description
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Sodium 5-amino-2-hydroxybenzoate is a specialized organic sodium salt derived from aminosalicylic acid, featuring the chemical formula C7H6NO3Na. Its unique structure combines an amino group at the fifth position and a hydroxyl group adjacent to the carboxylate moiety on the benzene ring, stabilized by the sodium cation. The compound is widely recognized in pharmaceutical and chemical research sectors for its versatile applications, particularly as an intermediate in the synthesis of complex heterocyclic compounds and dyes.
In the pharmaceutical industry, this molecule serves as a critical building block for developing various therapeutic agents. It is frequently utilized in the production of anti-inflammatory drugs and analgesics, where its specific substitution pattern allows for precise modification of biological activity. Furthermore, due to the presence of both nucleophilic amino and hydroxyl groups, it acts as an effective ligand in coordination chemistry, facilitating the formation of stable metal complexes used in catalytic processes. In analytical chemistry, derivatives of this compound are sometimes employed as indicators or chelating agents for metal ion detection.
The substance typically appears as a white to off-white crystalline powder, soluble in water and polar solvents, which enhances its utility in aqueous reaction systems. Its CAS number is 14098-89-0, providing a standardized reference for procurement and regulatory compliance across global supply chains. Safety data indicates that while generally stable under standard storage conditions, it should be handled with appropriate personal protective equipment to avoid skin or eye irritation, consistent with standard laboratory protocols for aromatic amines.
Industrial applications also extend to the textile sector, where it contributes to the synthesis of azo dyes requiring high colorfastness. Researchers value its reactivity profile for constructing substituted salicylamides and other nitrogen-containing heterocycles essential for modern medicinal chemistry. As demand for novel drug candidates grows, Sodium 5-amino-2-hydroxybenzoate remains a pivotal reagent in organic synthesis laboratories worldwide, bridging fundamental chemical theory with practical industrial manufacturing needs.