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<h3>Overview</h3>
<p>Sivelestat is a selective <strong>neutrophil elastase inhibitor</strong> primarily synthesized via chemical coupling. Its molecular formula is C<sub>17</sub>H<sub>20</sub>N<sub>4</sub>O<sub>5</sub>, and the CAS number is 166784-69-4.</p>
<h3>Application</h3>
<ul>
<li>Treatment of acute lung injury (ALI) in sepsis patients.</li>
<li>Management of systemic inflammatory response syndrome (SIRS).</li>
<li>Adjunct therapy for reducing neutrophil-mediated tissue damage during reperfusion.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with severe hypersensitivity to the compound. Requires storage below 25°C in a dry, dark environment. Clinical use must strictly adhere to dosage protocols to avoid bleeding risks or hepatic dysfunction.</p>