Category:
Advanced Intermediates
CAS NO:
486460-00-8
Standard:
In-house Standards,

Sitagliptin is an oral anti-hyperglycemic of the dipeptidyl peptidase-4(DPP-4) inhibitor class to treat diabetes mellitus type 2. By preventing GLP-1 and GIP inactivation, it is able to increase the secretion of insulin and suppress the release of glucagon by the pancreas, this drives blood glucose levels towards normal. Sitagliptin is a blockbuster drug with sales in excess of $6 Billion per year.