*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Sacubitril Hemicalcium salt is a calcium complex of the angiotensin receptor-neprilysin inhibitor (ARNI) sacubitril. Synthesized via coupling and neutralization processes, it serves as a critical intermediate for cardiovascular therapeutics. <strong>Molecular Formula</strong>: C42H56CaN4O10; <strong>CAS No.</strong>: 1017866-69-5.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing</strong>: Primary API intermediate for chronic heart failure treatment.</li>
<li><strong>Research & Development</strong>: Used in clinical trials to evaluate hemodynamic efficacy.</li>
<li><strong>Quality Control</strong>: Reference standard for potency testing in finished drug formulations.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at controlled temperatures below 25°C. Avoid contact with strong acids or bases. Personnel must utilize appropriate PPE to prevent respiratory irritation during handling.</p>