| CAS:188447-91-8 MF: C7H9NOS |
CBNumber: CB8166621
Molecular formula: C7H9NOS
Molecular weight: 155.22
MOL File: 188447-91-8. MOL
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<h3>Overview</h3>
<p>(S)-4-Methylbenzenesulfinamide (CAS 188447-91-8) is a chiral auxiliary defined by the <strong>molecular formula C7H9NO2S</strong>. Synthesized via asymmetric sulfinylation, it serves as a critical intermediate for constructing enantiopure amines in pharmaceutical manufacturing.</p>
<h3>Application</h3>
<ul>
<li><strong>Stereochemistry Control:</strong> Used in Evans-type auxiliaries to direct stereoselective alkylation and acylation reactions.</li>
<li><strong>Pharmaceutical Synthesis:</strong> Essential building block for synthesizing complex chiral drugs, including beta-blockers and antiviral agents.</li>
<li><strong>Asymmetric Catalysis:</strong> Functions as a ligand precursor in transition metal-catalyzed asymmetric hydrogenation.</li>
</ul>
<h3>Precautions</h3>
<ul>
<li><strong>Storage:</strong> Store under inert atmosphere at 2-8°C to prevent oxidation or hydrolysis.</li>
<li><strong>Safety:</strong> Handle with appropriate PPE; avoid contact with skin and eyes due to potential irritation.</li>
<li><strong>Regulatory:</strong> Not for direct human consumption; strictly for industrial research and development use only.</li>
</ul>