Product Description
(S)-2,3-Dihydro-1H-inden-1-ol、25501-32-0
AI Product Description
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(S)-2,3-Dihydro-1H-inden-1-ol is a specialized chiral building block widely utilized in the pharmaceutical and fine chemical industries for the synthesis of complex bioactive molecules. With the molecular formula C9H10O and a CAS registry number of 146785-36-6, this compound features a fused bicyclic structure consisting of a benzene ring fused to a cyclopentane ring, bearing a hydroxyl group at the chiral center. The specific stereochemistry denoted by the "(S)" prefix is critical, as it dictates the three-dimensional orientation of the molecule, which directly influences its biological activity and interaction with target receptors in drug discovery processes.
This enantiomerically pure alcohol serves as a versatile intermediate in organic synthesis. It is frequently employed as a precursor for constructing non-natural amino acids, chiral ligands for asymmetric catalysis, and various heterocyclic compounds. In medicinal chemistry, derivatives of (S)-2,3-dihydro-1H-inden-1-ol have been investigated for potential applications in treating neurological disorders, cardiovascular diseases, and inflammatory conditions due to their structural similarity to known pharmacophores. The presence of the hydroxyl group allows for further functionalization through esterification, etherification, or oxidation reactions, enabling chemists to tailor molecular properties for specific therapeutic needs.
Beyond pharmaceutical research, this chiral alcohol finds utility in the development of high-performance materials and agrochemicals where stereochemical purity is essential for efficacy and safety. Manufacturers typically supply this compound with high optical purity, often exceeding 98% enantiomeric excess, ensuring consistency in large-scale production. Its stability under standard storage conditions makes it a reliable reagent for laboratory-scale experiments and industrial manufacturing alike. As the demand for stereoselective synthesis grows, (S)-2,3-dihydro-1H-inden-1-ol remains a valuable asset for researchers aiming to develop next-generation therapeutics with improved selectivity and reduced side effects. Proper handling requires adherence to standard safety protocols, though it is generally considered stable when stored correctly away from moisture and strong oxidizing agents.