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Other Specialized Reagents

(S)-1-(4-fluorophenyl)ethanamine

Category:

Other Specialized Reagents

CAS NO:

66399-30-2

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

66399-30-2

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

(S)-1-(4-fluorophenyl)ethanamine、66399-30-2

AI Product Description

*The following content is generated by AI and is for reference only.

(S)-1-(4-fluorophenyl)ethanamine is a chiral organic compound characterized by a fluorinated phenyl ring attached to an ethylamine backbone with specific stereochemical configuration. Its molecular formula is C8H10FN, and it is identified by the CAS Registry Number 329-75-3. This enantiomerically pure substance serves as a critical intermediate in the pharmaceutical industry, particularly for the synthesis of biologically active amines and complex heterocyclic structures. The presence of the fluorine atom significantly enhances metabolic stability and lipophilicity, making derivatives containing this scaffold highly valuable in medicinal chemistry research. The primary application of (S)-1-(4-fluorophenyl)ethanamine lies in its role as a chiral building block for developing novel drug candidates. It is frequently utilized in the preparation of beta-blockers, antidepressants, and antihypertensive agents where the specific three-dimensional arrangement of atoms dictates biological efficacy and receptor binding affinity. The "S" designation ensures that only the desired stereoisomer is used, which is essential for meeting regulatory standards regarding drug purity and safety profiles. Furthermore, this compound finds utility in agrochemical synthesis, contributing to the development of new pesticides and herbicides with improved environmental compatibility. In laboratory settings, researchers employ this reagent for asymmetric synthesis protocols and chiral resolution studies. Its reactivity allows for versatile transformations, including reductive amination, acylation, and alkylation, facilitating the construction of diverse molecular architectures. Due to the increasing demand for precision medicine, high-purity chiral amines like this one are indispensable for producing single-enantiomer drugs that minimize side effects associated with racemic mixtures. While primarily an industrial chemical, it also supports academic investigations into structure-activity relationships (SAR). Handling requires standard safety precautions due to potential irritant properties, yet its unique structural features make it a cornerstone in modern organic synthesis for creating next-generation therapeutic agents targeting various human diseases.