rosuvastatin intermediates Z-8.1,,Active Pharmaceutical Ingredients,Cardiovascular System Drugs
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Product Description
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Rosuvastatin Intermediate Z-8.1 is a critical chiral building block for the synthesis of rosuvastatin calcium, a widely prescribed HMG-CoA reductase inhibitor. Manufactured via asymmetric hydrogenation or enzymatic resolution, this intermediate ensures high optical purity essential for pharmaceutical efficacy. Its molecular formula is <strong>C25H27FN2O6S</strong>, with CAS No. <strong>136902-47-7</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Primary precursor in large-scale production of rosuvastatin API.</li>
<li><strong>Clinical Therapy:</strong> Used to formulate lipid-lowering drugs for treating hyperlipidemia and preventing cardiovascular events.</li>
<li><strong>Quality Control:</strong> Serves as a reference standard for impurity profiling in finished drug formulations.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at 2-8°C to prevent degradation. Avoid direct skin contact; wear appropriate PPE including gloves and goggles. Do not ingest or inhale dust. Strictly adhere to GMP guidelines during handling to ensure patient safety and product consistency.</p>