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Other Specialized Reagents

(R)-2-Amino-3-methoxylpropanoic acid

Category:

Other Specialized Reagents

CAS NO:

86118-11-8

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

86118-11-8

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

(R)-2-Amino-3-methoxylpropanoic acid、86118-11-8

AI Product Description

*The following content is generated by AI and is for reference only.

(R)-2-Amino-3-methoxypropanoic acid is a specialized chiral amino acid derivative widely recognized in modern medicinal chemistry and pharmaceutical research. With the molecular formula C4H9NO3 and a CAS registry number of 1075-68-9, this compound serves as a critical building block for the synthesis of complex bioactive molecules. The molecule features a methoxy group substituted at the beta-position relative to the carboxylic acid, distinguishing it from standard alpha-amino acids like serine or threonine, while maintaining the essential (R)-stereochemistry required for high biological specificity. The primary application of (R)-2-amino-3-methoxypropanoic acid lies in the development of peptidomimetics and novel peptide therapeutics. Researchers utilize its unique structural properties to enhance the metabolic stability and oral bioavailability of drug candidates. By incorporating this non-natural amino acid into peptide backbones, scientists can improve resistance against proteolytic degradation, thereby extending the half-life of therapeutic agents in vivo. Furthermore, the methoxy moiety acts as a hydrogen bond acceptor mimic, allowing for precise modulation of receptor binding affinity and selectivity in target protein interactions. In addition to drug discovery, this chiral intermediate finds utility in the asymmetric synthesis of various heterocyclic compounds and complex natural products. Its availability in high enantiomeric purity makes it an invaluable reagent for academic laboratories and industrial R&D departments focused on creating next-generation antibiotics, antivirals, and anticancer agents. The compound is typically supplied as a white crystalline powder, stable under standard storage conditions but requiring protection from moisture to prevent hydrolysis. As the demand for precision medicine grows, the role of such stereochemically defined amino acid derivatives becomes increasingly pivotal in bridging the gap between theoretical design and clinical efficacy. Consequently, (R)-2-amino-3-methoxypropanoic acid remains a cornerstone material for advancing innovative pharmaceutical formulations and expanding the chemical space available for drug development.