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Other Specialized Reagents

Pyridine-3-boronic acid pinacol ester

Category:

Other Specialized Reagents

CAS NO:

329214-79-1

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

329214-79-1

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

Pyridine-3-boronic acid pinacol ester、329214-79-1

AI Product Description

*The following content is generated by AI and is for reference only.

Pyridine-3-boronic acid pinacol ester is a specialized organoboron compound widely utilized in modern organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its molecular formula is C10H14BN O2, reflecting a pyridine ring substituted at the third position with a boronic acid pinacol ester group. The compound is characterized by its stability under standard laboratory conditions, making it an ideal reagent for cross-coupling reactions that require mild handling and high functional group tolerance. The primary application of this molecule lies in Suzuki-Miyaura coupling reactions, where it serves as a crucial nucleophilic partner to couple with aryl or vinyl halides in the presence of a palladium catalyst. This reaction mechanism enables the formation of carbon-carbon bonds with exceptional efficiency and selectivity. Due to the presence of the pyridine heterocycle, the resulting coupled products often exhibit unique electronic properties and biological activities, which are highly desirable in drug discovery processes. Researchers frequently employ this ester to construct complex heteroaromatic scaffolds found in various bioactive molecules, including kinase inhibitors and anti-inflammatory agents. Beyond pharmaceutical development, Pyridine-3-boronic acid pinacol ester finds utility in materials science for synthesizing conductive polymers and organic light-emitting diodes (OLEDs). The pinacol ester moiety acts as a protecting group, preventing premature hydrolysis of the boronic acid functionality until the desired reaction conditions are met. This feature ensures high yields and purity in multi-step synthetic pathways. Furthermore, the compound is compatible with a wide range of solvents and bases, allowing for versatile optimization of reaction parameters. In summary, Pyridine-3-boronic acid pinacol ester represents a cornerstone reagent in contemporary medicinal chemistry and advanced material fabrication. Its robustness, combined with the strategic placement of the pyridine nitrogen, facilitates the efficient assembly of sophisticated molecular architectures. As the demand for novel therapeutic agents and functional materials grows, the role of this versatile boronate ester continues to expand, supporting innovation across diverse scientific disciplines through reliable and scalable synthetic methodologies.