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Preclinical Research Services
CAS NO:
145-14-2
Standard:
ChP,
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Basic Info
CAS Number
145-14-2
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Progesterone is a vital endogenous steroid hormone belonging to the progestogen class, playing a central role in the female reproductive system. Its chemical identity is defined by the molecular formula C21H30O2 and the CAS Registry Number 57-87-0. Structurally, it features a pregnane backbone with two ketone groups at positions three and twenty, distinguishing it from other steroid hormones like testosterone or estradiol. Naturally produced primarily by the corpus luteum in the ovaries during the luteal phase of the menstrual cycle, progesterone prepares the uterus for potential pregnancy by thickening the endometrial lining. If fertilization does not occur, levels drop, triggering menstruation; if fertilization occurs, it maintains the uterine environment essential for fetal development.
Beyond its physiological functions, synthetic and bioidentical progesterone are widely utilized in pharmaceutical applications. It serves as a cornerstone in hormonal replacement therapy (HRT) for menopausal women, helping to alleviate symptoms such as hot flashes, night sweats, and vaginal dryness while protecting the endometrium from hyperplasia when administered alongside estrogen. Furthermore, it is a critical component in various contraceptive formulations, including oral pills, patches, and intrauterine devices, where it inhibits ovulation and thickens cervical mucus to prevent sperm entry. In assisted reproductive technologies, progesterone supplementation is standard practice to support early pregnancy and reduce the risk of miscarriage.
In industrial and research contexts, progesterone acts as a key intermediate in the synthesis of other corticosteroids and sex hormones. Its versatility extends to veterinary medicine, where it regulates estrous cycles in livestock. Despite its therapeutic benefits, proper medical supervision is essential due to potential side effects, including dizziness, breast tenderness, and mood changes. As a naturally occurring molecule, bioidentical progesterone offers a favorable safety profile compared to some synthetic analogs, making it a preferred choice for many clinical protocols. Overall, this compound remains indispensable in modern medicine for regulating reproductive health and treating hormone-related disorders globally.
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