*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Posaconazole intermediate (POA) is a critical synthetic precursor for the antifungal drug posaconazole. It typically involves <strong>pyrimidine coupling</strong> and <strong>chiral resolution</strong> processes. Molecular formula: <strong>C25H28ClN5O2</strong>; CAS No.: <strong>171208-69-2</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing</strong>: Key raw material for large-scale synthesis of posaconazole tablets and IV formulations.</li>
<li><strong>R&D Laboratories</strong>: Used in stability testing and bioequivalence studies for new generic drugs.</li>
<li><strong>Contract Manufacturing</strong>: Sourced by CDMOs to produce active pharmaceutical ingredients (APIs).</li>
</ul>
<h3>Precautions</h3>
<p>Store under <strong>inert atmosphere</strong> at 2-8°C away from moisture. Personnel must wear <strong>nitrile gloves</strong> and eye protection due to potential irritancy. Not for direct human administration without further processing.</p>