1.Product name: Paracetamol & Diclofenac Sodium
2.Specification: paracetamol 500mg diclofenac sodium 50mg
3.Package: Box of 10 tablets
4.Shelf life: 36 months
5.Registration documents are available.
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*The following content is generated by AI and is for reference only.
Paracetamol and Diclofenac Sodium tablets represent a powerful combination analgesic therapy designed to manage moderate to severe pain, particularly in conditions involving both inflammatory and non-inflammatory components. This dual-action formulation leverages the synergistic effects of two distinct active ingredients: Paracetamol (also known as Acetaminophen) and Diclofenac Sodium. Paracetamol functions primarily as an antipyretic and mild analgesic by inhibiting prostaglandin synthesis in the central nervous system, effectively reducing fever and alleviating pain. In contrast, Diclofenac Sodium is a potent Non-Steroidal Anti-Inflammatory Drug (NSAID) that works peripherally to suppress inflammation, swelling, and pain at the site of injury by blocking cyclooxygenase enzymes.
This combination is commonly prescribed for acute musculoskeletal disorders such as sprains, strains, and soft tissue injuries, as well as for managing osteoarthritis, rheumatoid arthritis, and post-operative dental or surgical pain. The inclusion of Diclofenac allows for rapid reduction of inflammation that Paracetamol alone cannot address, while Paracetamol provides sustained pain relief with a lower risk of gastrointestinal irritation compared to NSAIDs used in isolation.
However, significant precautions must be observed when using this medication. It is strictly contraindicated for individuals with a history of peptic ulcers, gastrointestinal bleeding, severe heart failure, renal impairment, or hypersensitivity to aspirin and other NSAIDs. Patients taking anticoagulants should exercise extreme caution due to increased bleeding risks. Long-term use may elevate the risk of cardiovascular events, including heart attack or stroke, and can cause liver toxicity if the daily Paracetamol limit is exceeded. Users should never exceed the recommended dosage, typically limited to one tablet every eight hours, and must avoid alcohol consumption during treatment. Pregnant women, especially in the third trimester, and nursing mothers should consult a physician before use. Always follow medical advice regarding duration of therapy to minimize adverse effects.