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CAS NO:
127780-16-9
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Basic Info
CAS Number
127780-16-9
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Pantoprazole is a widely prescribed proton pump inhibitor (PPI) utilized primarily for the management of acid-related gastrointestinal disorders. Chemically known as 5-difluoromethoxy-2-[[3,4-dimethoxy-2-pyridinyl]methylsulfinyl]-1H-benzimidazole, it features the molecular formula C16H15F2N3O4S and carries the CAS Registry Number 108286-57-9. As a potent inhibitor of the gastric H+/K+-ATPase enzyme system, commonly referred to as the "proton pump," Pantoprazole effectively suppresses the final step of gastric acid production within the parietal cells of the stomach lining. This mechanism leads to a significant reduction in both basal and stimulated acid secretion, creating an environment conducive to healing damaged mucosal tissues.
The therapeutic applications of Pantoprazole are extensive and critical in modern gastroenterology. It is the first-line treatment for Gastroesophageal Reflux Disease (GERD), alleviating symptoms such as heartburn, regurgitation, and esophageal inflammation. Furthermore, it is indicated for the short-term treatment of erosive esophagitis and for maintaining healing in patients with this condition. Clinicians also prescribe it for the management of pathological hypersecretory conditions, including Zollinger-Ellison syndrome, where excessive acid production occurs due to gastrin-secreting tumors. In addition to these primary uses, Pantoprazole plays a vital role in preventing non-steroidal anti-inflammatory drug (NSAID)-associated gastric ulcers in high-risk patients and is often included in combination therapies for eradicating Helicobacter pylori infections, a major cause of peptic ulcer disease.
Available in various formulations, including delayed-release tablets and intravenous solutions, Pantoprazole offers flexibility in administration routes depending on patient needs and severity of the condition. Its pharmacokinetic profile allows for once-daily dosing, ensuring sustained acid suppression over a 24-hour period. While generally well-tolerated, long-term use requires monitoring for potential side effects such as hypomagnesemia, vitamin B12 deficiency, or bone density issues. Overall, Pantoprazole remains a cornerstone therapy in managing acid-peptic diseases, offering reliable efficacy and a favorable safety profile for millions of patients globally.
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