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Other Specialized Reagents

Palbociclib

Category:

Other Specialized Reagents

CAS NO:

184475-35-2

Standard:

ChP,In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Jianfeng Chemical Co., Ltd.

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Basic Info

CAS Number

184475-35-2

Pharmacopoeia

ChP,In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Aliase: 184475-35-2
Purity: 99%
Appearance:white powder
Usage: Gefitinib is an antineoplastic target therapy drug with relatively high specificity that was developed by the British
pharmaceutical company AstraZeneca, it is the first molecular targeted drug to be used in non-small cell lung cancer treatment.
Epidermal growth factors (EGF) are a kind of polypeptide with a relative molecular mass of 6.45x103, and they can bind with
epidermal growth factor receptors (EGFR) on target cell membrane surfaces to trigger biological effects. EGFR is a type of tyrosine kinase (TK) type receptor, so when bound with EGF, it will promote TK activation in the receptor. This will cause tyrosine residue in the receptor to autophosphorylate and send continuous dividing signals into the cell, causing cell proliferation and differentiation.EGFR is abundant in human tissue, and it is highly expressed in malign tumors. Geftinib blocks the signal transduction pathway of
cell surface EGFR to prevent tumor growth, metastasis, and growth in blood vessels, and it can induce tumor cell apoptosis. Gefitinib is mainly used to treat non-stem cell lung cancer.