*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Oxonic acid is a pyrimidine catabolite derived from uracil and thymine, primarily utilized as a specific inhibitor of dihydroorotate dehydrogenase (DHODH). The synthesis involves oxidative cleavage of pyrimidine rings. <strong>Molecular Formula</strong>: C<sub>4</sub>H<sub>3</sub>NO<sub>3</sub>; <strong>CAS No.</strong>: 1578-06-7.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Research</strong>: Used in vitro to study lymphocyte proliferation and autoimmune disease mechanisms via DHODH inhibition.</li>
<li><strong>Biochemical Analysis</strong>: Serves as a standard reference material for chromatography and metabolic pathway studies.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly for research use only; not approved for clinical therapy. Store under inert atmosphere at -20°C to prevent hydrolysis. Handle with appropriate PPE due to potential irritant properties.</p>