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CAS NO:
28721-07-5
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Basic Info
CAS Number
28721-07-5
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Oxcarbazepine is a widely prescribed anticonvulsant medication primarily utilized in the management of partial seizures with or without secondary generalization. Chemically, it serves as a 10-keto derivative of carbamazepine, designed to offer an improved therapeutic profile with potentially fewer drug-drug interactions and a more favorable side-effect spectrum. Its molecular formula is C₁₅H₁₂N₂O₂, reflecting its tricyclic structure which includes two benzene rings fused to a central heterocyclic system containing nitrogen and oxygen atoms. The substance is uniquely identified by the CAS Registry Number 28721-07-5, a critical identifier used globally for regulatory compliance, inventory management, and chemical safety documentation.
The primary clinical application of oxcarbazepine involves the treatment of epilepsy in both adults and children, typically aged four years and older. It functions by stabilizing hyperexcited nerve membranes, inhibiting repetitive neuronal firing through the blockade of voltage-sensitive sodium channels. This mechanism prevents the spread of seizure activity within the brain. Beyond epilepsy, it is sometimes employed off-label for mood stabilization in bipolar disorder, although this use requires careful medical supervision. Compared to its predecessor, carbamazepine, oxcarbazepine undergoes rapid metabolism into its active metabolite, 10-hydroxycarbazepine (MHD), which is responsible for most of the therapeutic effects. This metabolic pathway often results in reduced induction of hepatic enzymes, making it a preferred choice for patients on complex polypharmacy regimens.
Common side effects may include dizziness, somnolence, headache, and nausea. Serious but rare adverse reactions can involve hyponatremia or severe dermatological responses like Stevens-Johnson syndrome, necessitating regular monitoring of electrolyte levels and skin conditions during therapy. As a generic pharmaceutical product, it is available under various brand names worldwide, ensuring broad accessibility for patients requiring long-term seizure control. Its established efficacy and manageable safety profile continue to make it a cornerstone therapy in modern neurology and psychiatry, providing reliable symptom management for millions of individuals suffering from seizure disorders.
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