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CAS NO:
869477-96-3
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Basic Info
CAS Number
869477-96-3
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Olodaterol is a highly selective, long-acting beta2-adrenergic agonist (LABA) developed primarily for the management of chronic obstructive pulmonary disease (COPD). Chemically, it belongs to the class of arylpropylamine derivatives, distinguished by its unique molecular structure that ensures potent bronchodilation with minimal systemic side effects. The specific molecular formula of Olodaterol is C20H26N2O3, and it is identified by the CAS Registry Number 1059475-83-2. Its synthesis involves complex organic reactions designed to optimize receptor affinity while maintaining metabolic stability.
The primary clinical application of Olodaterol is the maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. Unlike short-acting agents used for acute relief, Olodaterol provides sustained bronchodilation over a 24-hour period, allowing for once-daily dosing regimens which significantly enhance patient adherence. By selectively stimulating beta2-adrenergic receptors on airway smooth muscle, it triggers a cascade that increases intracellular cyclic AMP, leading to muscle relaxation and widened airways. This mechanism effectively reduces dyspnea and improves lung function without causing significant tachycardia or tremors often associated with less selective beta-agonists.
Olodaterol is frequently utilized as a monotherapy or in combination with anticholinergic agents like tiotropium to maximize therapeutic outcomes in moderate-to-severe COPD. Clinical trials have demonstrated its efficacy in improving forced expiratory volume in one second (FEV1) and reducing the frequency of exacerbations. The drug is typically administered via an inhalation solution using a nebulizer system, ensuring direct delivery to the lungs. While generally well-tolerated, healthcare providers monitor patients for potential adverse events such as palpitations, hypokalemia, or paradoxical bronchospasm. As a cornerstone in modern respiratory care, Olodaterol represents a significant advancement in managing chronic lung diseases, offering patients improved quality of life through reliable, long-lasting symptom control. Its development underscores the ongoing evolution of targeted pharmacotherapies designed to address the specific physiological needs of individuals suffering from obstructive pulmonary conditions globally.
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