Category:
Antibiotics and Antiviral Preparations
CAS NO:
1400-61-9
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Basic Info
Is Manufacturer
No
Samples Provided
NO
Product Description
The prevention and treatment of candidal infections of the oral cavity, oesophagus and intestinal tract. The suspension provides effective prophylaxis against oral candidosis in those born of mothers with vaginal candidosis.
AI Product Description
*The following content is generated by AI and is for reference only.
Nystatin oral suspension, formulated at a concentration of 100,000 International Units per milliliter, is an antifungal medication specifically indicated for the treatment of localized candidal infections in the mouth and throat. This condition, commonly known as oral thrush, is caused by an overgrowth of *Candida* species, particularly *Candida albicans*. The medication is widely prescribed for infants, children, and adults who are immunocompromised or have been treated with broad-spectrum antibiotics that disrupt normal flora balance. Nystatin functions by binding to sterols in the fungal cell membrane, creating pores that lead to leakage of intracellular contents and subsequent cell death. Crucially, it is not absorbed systemically when taken orally; therefore, it acts locally within the gastrointestinal tract without affecting internal organs or causing significant systemic toxicity.
Administration typically involves shaking the bottle well before use to ensure uniform distribution of the active ingredient. For optimal efficacy, the suspension should be swished around the mouth and held there for as long as possible before swallowing. Treatment duration usually spans several days after symptoms have resolved to prevent recurrence. Patients must adhere strictly to the prescribed dosage schedule, which varies based on age and severity of infection. Common side effects are rare but may include nausea, vomiting, or diarrhea if the medication is swallowed in large quantities. Allergic reactions, though uncommon, can manifest as skin rashes or difficulty breathing and require immediate medical attention.
Important precautions include avoiding use in patients with a known hypersensitivity to nystatin or any component of the formulation. It is generally safe for use during pregnancy and lactation due to its lack of systemic absorption, though consultation with a healthcare provider is advised. The product should be stored at room temperature, protected from light, and kept out of reach of children. Do not use this medication for systemic fungal infections, as it is ineffective against them. If symptoms persist beyond one week of therapy or worsen, medical evaluation is necessary to rule out resistant strains or alternative diagnoses. Proper hygiene practices, such as cleaning dentures and pacifiers, complement pharmacological treatment to ensure complete eradication of the infection.
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