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Other Specialized Reagents

N,N-Dimethylformamide dimethyl acetal

Category:

Other Specialized Reagents

CAS NO:

4637-24-5

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Show Room

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Basic Info

CAS Number

4637-24-5

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

N,N-Dimethylformamide dimethyl acetal、4637-24-5

AI Product Description

*The following content is generated by AI and is for reference only.

N,N-Dimethylformamide dimethyl acetal (DMF-DMA) is a versatile and highly reactive chemical reagent widely utilized in organic synthesis, pharmaceutical manufacturing, and materials science. With the molecular formula C5H13NO2 and a CAS registry number of 4637-24-5, this colorless to pale yellow liquid serves as a crucial building block for constructing complex heterocyclic structures. Its unique chemical structure features an acetal functionality attached to a dimethylformamide backbone, rendering it exceptionally electrophilic at the carbonyl carbon while maintaining stability under specific conditions. The primary application of DMF-DMA lies in its ability to act as a formylating agent. It is extensively employed to introduce formyl groups into various substrates, facilitating the synthesis of amides, imines, and enamines. In the pharmaceutical industry, it is indispensable for producing active pharmaceutical ingredients (APIs), particularly those containing pyrimidine, pyrazole, and quinoline rings. For instance, it plays a pivotal role in the synthesis of antiviral drugs and anticancer agents where precise functional group manipulation is required. Furthermore, DMF-DMA is frequently used as a starting material for generating N,N-dimethylformamides and other valuable intermediates in fine chemical production. Beyond pharma, this reagent finds utility in the development of advanced materials, including polymers and dyes. Its high reactivity allows for efficient reactions under mild conditions, often reducing reaction times and improving overall yields compared to traditional formylation methods. However, due to its potential toxicity and irritant properties, strict safety protocols must be observed during handling. Proper ventilation, personal protective equipment, and adherence to storage guidelines are essential to mitigate risks associated with inhalation or skin contact. The compound should be stored in a cool, dry place away from incompatible substances such as strong oxidizers and acids to prevent decomposition or hazardous reactions. In summary, N,N-Dimethylformamide dimethyl acetal remains a cornerstone reagent in modern synthetic chemistry. Its efficiency in introducing formyl moieties and constructing nitrogen-containing heterocycles makes it invaluable for researchers and industrial chemists alike. As demand grows for novel therapeutic compounds and specialized materials, the importance of DMF-DMA in accelerating chemical innovation continues to expand, solidifying its status as an essential tool in the global chemical supply chain.