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Other Specialized Reagents

N,N-Dimethylacetamide dimethyl acetal

Category:

Other Specialized Reagents

CAS NO:

18871-66-4

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

18871-66-4

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

N,N-Dimethylacetamide dimethyl acetal、18871-66-4

AI Product Description

*The following content is generated by AI and is for reference only.

N,N-Dimethylacetamide dimethyl acetal is a specialized organic reagent widely utilized in synthetic chemistry as a versatile methylating and formylating agent. Its molecular formula is C6H13NO2, and it carries the CAS registry number 5974-28-7. Structurally, this compound consists of a dimethylamino group attached to an acetal carbon, which is further substituted with two methoxy groups. This unique configuration allows it to serve as a stable source of reactive intermediates under controlled conditions, making it highly valuable for transforming various functional groups in complex molecular architectures. In laboratory and industrial applications, N,N-Dimethylacetamide dimethyl acetal is primarily employed for the introduction of formyl or methyl groups onto nucleophilic substrates. It acts as an efficient alternative to more hazardous or volatile reagents like dimethylformamide dimethyl acetal (DMFDMA), offering improved stability and ease of handling. Researchers frequently utilize this acetal in the synthesis of heterocyclic compounds, including pyridines, quinolines, and other nitrogen-containing rings, where it facilitates cyclization reactions with high regioselectivity. Additionally, it plays a crucial role in the preparation of pharmaceutical intermediates and agrochemicals, contributing to the development of new therapeutic agents and crop protection products. The reagent is typically available as a clear, colorless liquid that is soluble in common organic solvents such as dichloromethane, tetrahydrofuran, and ethanol. While it exhibits good thermal stability compared to many other acetals, standard safety precautions should be observed during handling, as it may release methanol upon hydrolysis. Proper storage in a cool, dry place away from moisture and strong acids is essential to maintain its integrity. Due to its specific reactivity profile, it has become a staple in modern organic synthesis protocols, enabling chemists to construct complex molecules with greater efficiency and yield. Whether used in academic research or large-scale manufacturing, N,N-Dimethylacetamide dimethyl acetal remains a critical tool for advancing chemical innovation across diverse sectors.