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Products

Active Pharmaceutical Ingredients

Neomycin Sulfate Ointment

Category:

Active Pharmaceutical Ingredients

CAS NO:

1405-10-3

Standard:

BP,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Tianjin Sinomed Pharmaceutical Co., Ltd.

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Basic Info

CAS Number

1405-10-3

Pharmacopoeia

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Samples Provided

Packaging & Delivery

Packaging Specification

1 tube/box

Product Description

1.Product name:Neomycin Sulfate Ointment

2.Specification: Each gram of ointment contains Neomycin 5000units

3.Package:1 tube/box

4.Shelf life:36 months

5.Registration documents are available.

If you are interested in our products,please feel free to contact us.

AI Product Description

*The following content is generated by AI and is for reference only.

Neomycin Sulfate Ointment is a widely utilized topical antibiotic formulation designed to treat and prevent bacterial skin infections. The active pharmaceutical ingredient, Neomycin Sulfate, possesses the molecular formula C23H46N6O13S and is identified by the CAS Registry Number 1405-10-3. This aminoglycoside antibiotic functions by binding irreversibly to the 30S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis and leading to bacterial cell death. It demonstrates broad-spectrum activity against both Gram-positive organisms, such as Staphylococcus aureus, and many Gram-negative bacteria, including Escherichia coli and Proteus species. Clinically, this ointment is primarily indicated for the management of secondary bacterial infections complicating minor cuts, burns, scrapes, and surgical wounds. It is also frequently prescribed for conditions like impetigo, infected dermatitis, and infected eczema where bacterial colonization is evident. The base of the ointment typically consists of petrolatum or similar emollients, which facilitate drug delivery while maintaining moisture at the application site, promoting healing. Unlike systemic antibiotics, topical neomycin minimizes systemic absorption, reducing the risk of nephrotoxicity or ototoxicity associated with intravenous administration; however, local hypersensitivity reactions remain a significant concern. Despite its efficacy, the use of Neomycin Sulfate Ointment requires caution due to the rising prevalence of contact dermatitis caused by neomycin sensitivity. Patients experiencing redness, itching, or swelling after application should discontinue use immediately. Furthermore, prolonged use can lead to the emergence of resistant bacterial strains or superinfections with non-susceptible organisms, including fungi. Consequently, medical guidelines recommend limiting treatment duration to seven days unless directed otherwise by a healthcare provider. While effective for superficial infections, it is not suitable for deep puncture wounds, animal bites, or severe burn areas without professional evaluation. Overall, Neomycin Sulfate Ointment remains a staple in dermatological care for short-term bacterial control when used responsibly under medical supervision.