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152658-17-8
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Basic Info
CAS Number
152658-17-8
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Nalfurafine is a selective kappa-opioid receptor agonist developed for managing refractory pruritus. The core synthesis involves complex organic coupling reactions. Its molecular formula is <strong>C<sub>24</sub>H<sub>30</sub>N<sub>2</sub>O<sub>3</sub></strong> and CAS number is <strong>165879-57-8</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Dermatology:</strong> Treatment of uremic pruritus in hemodialysis patients.</li>
<li><strong>Nephrology:</strong> Management of chronic itch associated with end-stage renal disease.</li>
<li><strong>Pharmaceutical Manufacturing:</strong> Active Pharmaceutical Ingredient (API) production for oral tablets.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated in severe hepatic impairment. Storage requires controlled room temperature below 25°C in dry, light-resistant containers to maintain chemical stability and potency.</p>
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