Product Description
N-Arachidonoyl serotonin
Type : griffonia seed extract
Appearance :powder
Part : seed
Extraction Method : Solvent Extraction
Packing : bottle , drum , vacuum packed
Grade :medicine grade
Molecular formula : N30H42N2O2
Function :
1. Inhibitors of fatty acid amide hydrolase (FAAH).
2. It has analgesic effect on rodents.
Contact :
Trading manger : Helen Tan
Whatsapp : +86 13930229229
Website : www.blrhbio.com
AI Product Description
*The following content is generated by AI and is for reference only.
N-Arachidonoyl serotonin (AA-5HT), identified by CAS number 187947-37-1, is a specialized bioactive lipid mediator belonging to the family of N-acylethanolamines and serotonin derivatives. This compound represents a unique intersection between the endocannabinoid system and serotonergic signaling pathways, functioning as a hybrid molecule that combines an arachidonic acid tail with a serotonin head group. Its primary utility lies in advanced biomedical research, particularly within the fields of neuropharmacology, inflammation studies, and pain management.
In laboratory settings, AA-5HT serves as a critical tool for investigating receptor interactions, specifically targeting transient receptor potential vanilloid type 1 (TRPV1) channels and various serotonin receptors. Research indicates that this molecule acts as an agonist at TRPV1, influencing calcium influx and neuronal excitability, which makes it invaluable for studying sensory neuron physiology and nociception. Furthermore, its role in modulating inflammatory responses offers insights into potential therapeutic targets for chronic pain conditions and neurodegenerative disorders. Scientists utilize high-purity AA-5HT to elucidate complex signaling cascades involving lipid mediators, helping to distinguish its specific effects from related compounds like anandamide or N-arachidonoyl dopamine.
Handling this reagent requires strict adherence to safety protocols. Although primarily intended for in vitro experimentation, researchers must treat AA-5HT as a potent biological agent. It should be stored under inert atmospheres at ultra-low temperatures, typically -20°C or lower, to prevent oxidative degradation and hydrolysis, which can compromise its structural integrity and experimental validity. Personal protective equipment, including gloves and lab coats, is mandatory during manipulation to avoid skin contact or accidental ingestion. As a research chemical, it is strictly designated for laboratory use only and is not approved for human consumption, veterinary applications, or clinical therapies. Proper disposal procedures must follow institutional guidelines for hazardous biological waste. By maintaining rigorous quality control and safety standards, researchers can effectively leverage AA-5HT to advance our understanding of lipid-mediated signaling in health and disease.