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Other Specialized Reagents

Montelukast sodium

Category:

Other Specialized Reagents

CAS NO:

151767-02-1

Standard:

EP,In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Jianfeng Chemical Co., Ltd.

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Basic Info

CAS Number

151767-02-1

Pharmacopoeia

EP,In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Aliase: Montelukast sodium
Purity: 99%
Appearance:White to off-white cnystalline powder
Brand: jianfeng
price: attractive and reasonable price
Usage: It can be applied to alleviate the symptoms caused by allergic rhinitis.

AI Product Description

*The following content is generated by AI and is for reference only.

Montelukast sodium is a potent and selective leukotriene receptor antagonist (LTRA) widely utilized in the management of asthma and allergic rhinitis. Chemically known as 1-[[[1-[3-(2-chlorophenyl)-3-(1,1-dimethylethyl)-1H-pyrazol-5-yl]methyl]-2-hydroxyphenyl]methyl]-4-methyl-6,7,8,9-tetrahydro-1H-pyrazolo[4,3-c]pyridine-5-carboxylic acid, monosodium salt, it possesses the molecular formula C35H36ClN3O3S·Na. Its corresponding CAS Registry Number is 159789-10-7. This pharmaceutical agent functions by specifically blocking the cysteinyl leukotriene type 1 (CysLT1) receptor. Leukotrienes are inflammatory mediators released during allergic reactions that cause bronchoconstriction, increased mucus production, and airway edema. By inhibiting these pathways, Montelukast sodium effectively reduces airway inflammation and prevents the symptoms associated with respiratory distress. Clinically, this medication is primarily indicated for the prophylaxis and chronic treatment of asthma in adults and children aged one year and older. It is particularly valuable for patients experiencing exercise-induced bronchoconstriction when taken prior to physical activity. Furthermore, it is approved for the relief of symptoms associated with seasonal and perennial allergic rhinitis, including sneezing, nasal congestion, and runny nose. Unlike short-acting beta-agonists used for acute attacks, Montelukast sodium is not intended for the reversal of acute bronchospasm but serves as a maintenance therapy to improve overall lung function and quality of life. The drug is typically administered orally once daily, usually in the evening, due to the circadian rhythm of leukotriene release. While generally well-tolerated, clinicians monitor patients for potential neuropsychiatric events, such as mood changes or sleep disturbances, which have been reported in rare cases. As a cornerstone in modern allergy and asthma care, Montelukast sodium offers a convenient, non-inhaled option that significantly enhances patient compliance and long-term disease control across diverse demographics.