Description:EIDD-2801 is an orally bioavailable isopropylester prodrug of the ribonucleoside analog EIDD-1931. EIDD-2801 shows anti-influenza virus and coronaviruses activities. EIDD-2801 has the potential for seasonal and pandemic influenza treatment.
In Vivo:EIDD-2801 (7 mg/kg; oral; twice daily for 3.5 days) significantly reduces shed virus load and duration of fever[1]. Animal Model: Ca/09-infected female ferrets[1] Dosage: 7 mg/kg Administration: Oral; twice daily for 3.5 days Result: Shed virus load and duration of fever were significantly reduced.
Melting point :156 - 159°C
storage temp:-20°C, Inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White