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<h3>Overview</h3>
<p>Minoxidil sulphate (CAS <strong>83701-22-8</strong>) is the sulfate salt derivative of minoxidil, primarily utilized as an intermediate in pharmaceutical synthesis. Its molecular formula is C9H15N5O4S. The core manufacturing process involves the sulfation reaction of minoxidil with sulfuric acid or chlorosulfonic acid under controlled conditions to ensure high purity and stability for downstream drug formulations.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Intermediates:</strong> Serves as a critical precursor for synthesizing Minoxidil tartrate and other active pharmaceutical ingredients (APIs) targeting alopecia.</li>
<li><strong>Research & Development:</strong> Employed in laboratory studies investigating vasodilatory mechanisms and cardiovascular therapeutic pathways.</li>
<li><strong>Custom Manufacturing:</strong> Used by contract development and manufacturing organizations (CDMOs) for specialized dosage form production.</li>
</ul>
<h3>Precautions</h3>
<p>This compound requires storage in a cool, dry, and well-ventilated area away from incompatible oxidizers. Personnel must wear appropriate PPE including gloves and eye protection during handling due to potential skin irritation. It is strictly an industrial intermediate and not intended for direct clinical administration without further processing.</p>