Category:
Finished Dosage
CAS NO:
443-48-1
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Basic Info
Is Manufacturer
YES
Samples Provided
NO
Packaging & Delivery
Packaging Specification
1 bottle/box
Product Description
1.Product name: Metronidazole Infusion
2.Specification: 500mg/100ml
3.Package: 1 bottle/box
4.Shelf life: 36 months
5.Registration documents are available.
If you are interested in our products,please feel free to contact us
AI Product Description
*The following content is generated by AI and is for reference only.
Metronidazole Infusion is a sterile, intravenous antibiotic solution widely utilized in clinical settings to treat severe anaerobic bacterial infections and certain protozoal diseases. As a nitroimidazole derivative, it functions by penetrating microbial cells and disrupting their DNA synthesis, effectively halting replication and leading to cell death. This formulation is particularly indicated for conditions such as intra-abdominal infections (including peritonitis and liver abscesses), pelvic inflammatory disease, bacterial vaginosis, Clostridioides difficile colitis, and brain abscesses caused by susceptible anaerobes. It is also the treatment of choice for amebiasis and trichomoniasis when oral administration is not feasible due to patient condition or absorption issues.
The infusion is typically administered slowly via an IV drip over 30 to 60 minutes to minimize adverse reactions. Dosage varies significantly based on the severity of the infection, patient age, renal function, and specific pathogen involved. Common side effects include nausea, vomiting, metallic taste, headache, and dizziness. A critical safety warning involves the risk of peripheral neuropathy with prolonged use, necessitating careful monitoring during extended therapy courses. Furthermore, patients must strictly avoid consuming alcohol during treatment and for at least 72 hours after the final dose, as concurrent intake can trigger a severe disulfiram-like reaction characterized by flushing, tachycardia, hypotension, and vomiting.
Special caution is required for patients with a history of blood dyscrasias or central nervous system disorders. While generally safe, Metronidazole Infusion may interact with anticoagulants like warfarin, potentially increasing bleeding risks, and should be used with care in pregnant women, particularly during the first trimester, unless the benefit clearly outweighs the potential risk to the fetus. Healthcare providers must ensure proper hydration and monitor complete blood counts during long-term therapy. Overall, while highly effective against resistant anaerobes, this medication demands strict adherence to dosing protocols and patient counseling regarding lifestyle restrictions to ensure therapeutic success and patient safety.
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