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Finished Dosage
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364-62-5
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Basic Info
Is Manufacturer
YES
Samples Provided
NO
Packaging & Delivery
Packaging Specification
Box of 10 ampoules/tray/box
Product Description
1.Product name: Metoclopramide Injection
2.Specification: 10mg/2ml
3.Package: Box of 10 ampoules/tray/box
4.Shelf life: 36 months
5.Registration documents are available.
If you are interested in our products,please feel free to contact us
AI Product Description
*The following content is generated by AI and is for reference only.
Metoclopramide Injection is a potent pharmaceutical agent primarily utilized for the management of nausea and vomiting associated with gastroesophageal reflux disease (GERD), chemotherapy, radiation therapy, and postoperative recovery. Classified as a dopamine antagonist and a prokinetic agent, it functions by blocking dopamine receptors in the chemoreceptor trigger zone of the brain while simultaneously enhancing gastric motility and accelerating gastric emptying. This dual mechanism makes it particularly effective for patients suffering from gastroparesis or severe gastrointestinal dysmotility where rapid relief is necessary.
The injection formulation is typically administered intravenously or intramuscularly in clinical settings, offering a rapid onset of action compared to oral preparations. It is frequently employed in emergency departments and surgical units to provide immediate symptomatic relief when oral intake is not feasible. However, its use requires strict medical supervision due to a significant safety profile concerning neurological side effects. The most critical warning involves the risk of tardive dyskinesia, a potentially irreversible movement disorder characterized by involuntary facial and body movements. Consequently, regulatory agencies recommend limiting treatment duration to no more than twelve weeks and avoiding long-term maintenance therapy whenever possible.
Additional precautions include monitoring for extrapyramidal symptoms such as dystonia, akathisia, and parkinsonism, which are more common in young adults and children. Patients with a history of epilepsy, pheochromocytoma, or gastrointestinal obstruction should generally avoid this medication, as it may exacerbate these conditions. Furthermore, Metoclopramide can interact adversely with other central nervous system depressants, necessitating careful dosage adjustments. Pregnant or breastfeeding women require specific risk-benefit assessments before administration. While highly effective for acute symptom control, clinicians must weigh the therapeutic benefits against the potential for serious adverse reactions, ensuring that the lowest effective dose is used for the shortest duration necessary to achieve clinical goals. Proper patient education regarding potential side effects is essential for safe utilization.
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