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<h3>Overview</h3>
<p><strong>Methyl 3-fluoro-4-hydroxyphenylacetate</strong> is a specialized fluorinated ester intermediate synthesized via selective fluoroalkylation and methoxylation. Its molecular formula is C9H9FO3 (CAS No. 100465-28-7), serving as a critical building block for advanced pharmaceutical synthesis.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceuticals: Precursor for fluorinated NSAIDs and cardiovascular agents.</li>
<li>Agrochemicals: Intermediate in developing herbicides with enhanced metabolic stability.</li>
<li>Research: Used in medicinal chemistry libraries for SAR studies on phenolic derivatives.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at 2-8°C to prevent hydrolysis. Avoid direct skin contact due to potential irritancy; handle in fume hoods with appropriate PPE. Not approved for direct clinical use as a drug substance.</p>