Product Description
Methyl 2-(2-aminophenyl)acetate、35613-44-6
AI Product Description
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Methyl 2-(2-aminophenyl)acetate is a specialized organic compound widely recognized in the fields of medicinal chemistry and fine chemical synthesis. With the molecular formula C9H11NO2 and a CAS Registry Number of 35684-70-7, this molecule serves as a versatile intermediate for constructing complex heterocyclic structures. Its chemical architecture features an ester group attached to an acetic acid backbone, which is further substituted with an ortho-amino phenyl ring. This specific arrangement provides unique reactivity patterns, allowing chemists to engage in diverse transformations such as cyclization reactions, condensation processes, and nucleophilic substitutions.
The primary application of Methyl 2-(2-aminophenyl)acetate lies in the pharmaceutical industry, where it acts as a crucial building block for synthesizing biologically active compounds. It is frequently utilized in the production of benzodiazepines, quinolones, and various other nitrogen-containing heterocycles that exhibit significant pharmacological properties, including anti-inflammatory, analgesic, and antimicrobial activities. The presence of both the amino and ester functionalities enables the formation of lactams and other cyclic systems essential for drug development pipelines. Furthermore, researchers employ this reagent in materials science to explore novel polymers or functional dyes requiring precise aromatic substitution patterns.
Safety protocols are paramount when handling this substance. As with many organic amines and esters, it should be stored in a cool, dry place away from strong oxidizing agents and incompatible chemicals to prevent degradation or hazardous reactions. Proper personal protective equipment, including gloves and eye protection, is recommended during laboratory manipulation to avoid skin contact or inhalation of vapors. While not classified as a highly toxic substance under general regulations, standard industrial hygiene practices must be observed. Its availability from specialized chemical suppliers makes it accessible for academic research and industrial scale-up projects aiming to develop next-generation therapeutic agents or advanced functional materials. Ultimately, Methyl 2-(2-aminophenyl)acetate remains an indispensable tool for chemists seeking efficient pathways to synthesize high-value nitrogenous heterocycles.