Category:
Other Anti-Infective Drug
CAS NO:
59-05-2
Standard:
ChP,USP,EP,
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Basic Info
CAS Number
59-05-2
Pharmacopoeia
ChP,USP,EP
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Samples Provided
YES
Packaging & Delivery
Packaging Specification
25KG/drum
Minimum Order Quantity
1kg
Delivery Cycle
within 7 days after payment
Product Description
Product Name: Methotrexate
CAS No.: 59-05-2
Chemical Name:
L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methyl-amino]benzoyl]-;
L-(+)-N-[p-[[2,4-diamino-6-pteridinyl)methylamino]benzoyl] glutamic acid;
(S)-2-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid
Standard/Specification: CP/USP/BP/EP
Appearance: a yellow to orange, crystalline powder
Assay: 98%~102%
Water: not more than 12%
Storage: preserve in tight, light-resistant containers.
Methotrexate is a drug with a wide range of clinical applications. Here's a look at how it works: # # # # mechanism of action - As a folate antagonist, metotrexate has a high affinity with the dihydrofolate reductase enzyme, which when combined prevents dihydrofolates from being reduced to tetrahydrofolate. Tetrahydrofolate is an important coenzyme within the cell that is involved in the synthesis of purine nucleotide and pyridine nucleotide. Methotrexate inhibits the synthesis of DNA, RNA and opal by inhibiting the production of tetrahydrofolate, and ultimately inhibits cell proliferation and division.
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