*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Memantine Related Compound E</strong> is a synthetic impurity of the NMDA receptor antagonist Memantine. It serves as a critical reference standard for quality control in pharmaceutical manufacturing. The molecular formula is C12H24N2O and its CAS number is 60539-67-3.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical R&D: Used as an analytical standard to validate HPLC methods during drug substance development.</li>
<li>Quality Assurance: Employed in impurity profiling to ensure compliance with ICH guidelines in finished dosage forms.</li>
<li>Toxicology Studies: Utilized in safety assessments to evaluate potential genotoxicity of process-related byproducts.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent degradation. Handle with appropriate PPE including nitrile gloves and eye protection. Do not use in clinical settings; strictly limited to laboratory research and industrial quality analysis.</p>