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CAS NO:
61-68-7
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ChP,
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Basic Info
CAS Number
61-68-7
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Mefenamic acid is a widely utilized non-steroidal anti-inflammatory drug (NSAID) belonging to the anthranilic acid derivative class. Chemically, it is characterized by the molecular formula C15H15NO2 and carries the CAS Registry Number 61-68-7. Its chemical structure features two phenyl rings linked to an amide group with a methyl substituent, which contributes to its specific pharmacological profile. This compound acts primarily by inhibiting cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins, which are key mediators of inflammation, pain, and fever in the human body.
Clinically, mefenamic acid is most frequently prescribed for the management of mild to moderate pain, particularly dysmenorrhea, where it has demonstrated significant efficacy in alleviating menstrual cramps and associated symptoms. Beyond gynecological applications, it is also effective in treating other types of acute pain, such as dental pain, musculoskeletal disorders, and post-operative discomfort. Additionally, due to its anti-prostaglandin properties, it helps reduce excessive menstrual bleeding. The drug is typically administered orally in capsule or tablet form, offering rapid onset of action that makes it suitable for acute symptom relief.
While generally well-tolerated, like all NSAIDs, mefenamic acid carries potential risks including gastrointestinal irritation, ulceration, and bleeding, especially with long-term use. Patients with a history of peptic ulcer disease, asthma, or renal impairment require careful monitoring. It should be avoided during the third trimester of pregnancy due to the risk of premature closure of the ductus arteriosus. Despite these considerations, mefenamic acid remains a cornerstone therapy in pain management protocols worldwide, valued for its balance between analgesic potency and safety when used appropriately under medical supervision. Its availability in various formulations ensures accessibility for diverse patient needs across global healthcare systems.
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