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Preclinical Research Services
CAS NO:
70374-39-9
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ChP,
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Basic Info
CAS Number
70374-39-9
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Lornoxicam is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the oxicam class of pyrazolone derivatives. Chemically, it possesses the molecular formula C15H13ClN4O4S and carries the unique identifier CAS number 70627-98-2. This compound functions primarily by inhibiting cyclooxygenase enzymes, specifically COX-1 and COX-2, which are critical for the biosynthesis of prostaglandins. By blocking these enzymes, Lornoxicam effectively reduces inflammation, alleviates pain, and lowers fever, making it a valuable therapeutic agent in clinical settings worldwide.
The primary medical applications of Lornoxicam involve the management of moderate to severe acute pain and inflammatory conditions. It is frequently prescribed for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and various musculoskeletal disorders such as low back pain, sprains, and strains. Additionally, it is often utilized for post-operative pain relief following dental or orthopedic surgeries due to its rapid onset of action and high potency. Clinicians appreciate Lornoxicam for its strong analgesic properties, which are comparable to those of morphine in certain contexts but without the associated risk of respiratory depression or addiction common with opioids.
Pharmacokinetically, Lornoxicam exhibits good oral bioavailability and reaches peak plasma concentrations relatively quickly after administration. Its half-life ranges from approximately three to four hours, allowing for flexible dosing schedules, typically twice daily. While generally well-tolerated, like other NSAIDs, it carries potential risks including gastrointestinal irritation, ulceration, and increased bleeding tendencies. Patients with a history of peptic ulcers, renal impairment, or cardiovascular disease require careful monitoring when prescribed this medication. Despite these considerations, Lornoxicam remains a cornerstone in modern pain management protocols, offering an effective balance between efficacy and safety for a wide spectrum of inflammatory and painful conditions. Its widespread availability in tablet, injectable, and suppository forms ensures accessibility across diverse healthcare environments globally.
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