*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Lodoxamide is a potent mast cell stabilizer used in ophthalmology. Its core synthesis involves heterocyclic coupling reactions to form the <strong>dihydrochloride salt</strong>. The chemical formula is C<sub>16</sub>H<sub>15</sub>ClN<sub>4</sub>O<sub>2</sub>, and the CAS number is 7089-87-8.</p>
<h3>Application</h3>
<ul>
<li><strong>Ophthalmic Formulations:</strong> Treatment of vernal keratoconjunctivitis and allergic conjunctivitis.</li>
<li><strong>Pharmaceutical Intermediates:</strong> Used as a reference standard for quality control in drug manufacturing.</li>
<li><strong>Research Reagents:</strong> Applied in studies regarding inflammatory mediator release inhibition.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with known hypersensitivity to lodoxamide or its excipients. Store under controlled room temperature (20-25°C) in tightly sealed containers protected from light and moisture to maintain stability.</p>