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Other Specialized Reagents

lamivudine Cas 134678-17-4 from China

Category:

Other Specialized Reagents

CAS NO:

134678-17-4

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Jianfeng Chemical Co., Ltd.

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Basic Info

CAS Number

134678-17-4

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Aliase: lamivudine Cas 134678-17-4 from China
Purity: 99.0%min
Appearance:Powder
Brand: Crovell
Usage: Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.

AI Product Description

*The following content is generated by AI and is for reference only.

Lamivudine, identified by the CAS number 134678-17-4, is a widely utilized synthetic nucleoside reverse transcriptase inhibitor (NRTI) produced in China for global pharmaceutical markets. Chemically known as (-)-cis-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)cytosine, its molecular formula is C8H11N3O3S and it possesses a molecular weight of approximately 229.26 g/mol. This compound features a unique oxathiolane ring structure that mimics natural nucleosides, allowing it to effectively interfere with viral replication processes without significantly affecting host cell DNA synthesis. The primary clinical application of Lamivudine is the treatment of Human Immunodeficiency Virus (HIV-1) infections. It functions by inhibiting the enzyme reverse transcriptase, thereby preventing the conversion of viral RNA into DNA, which halts the proliferation of the virus within human cells. Furthermore, it serves as a cornerstone therapy for chronic Hepatitis B Virus (HBV) infections, where it suppresses viral load and reduces liver damage associated with long-term infection. In many regions, particularly in China, Lamivudine is manufactured at scale to meet high international demand, often supplied as a raw active pharmaceutical ingredient (API) for formulation into tablets, oral solutions, or combination therapies like tenofovir/lamivudine/emtricitabine regimens. Beyond its therapeutic roles, this chemical entity is frequently used in research settings to study antiviral mechanisms, drug resistance mutations, and pharmacokinetic profiles. The availability of high-purity Lamivudine from Chinese manufacturers ensures cost-effective access to essential HIV and HBV treatments worldwide, supporting global public health initiatives. Its safety profile, when used according to medical guidelines, is well-established, making it a preferred choice for both pediatric and adult patients. As a critical component of antiretroviral therapy, Lamivudine continues to play an indispensable role in managing retroviral diseases, offering significant improvements in life expectancy and quality of life for millions of patients globally.